Consortium

The Netherlands Cancer Institute (NKI, The Netherlands), the Coordinator of the NTI , hosts the project “The relationship between structural and numerical chromosomal instability”, and trains one ESR in association with the University of Utrecht. Furthermore the NKI is one of the lead institutions in the training courses “Time-lapse imaging and FRET “, “Assay Development for High-Throughput Screening “ and “Computational biology and Bioinformatics“.

The University Medical Center Groningen (UMCG, The Netherlands), hosts the project “Mouse models to monitor chromosome segregation in aneuploid tumours by intravital imaging”, and trains one ESR in association with the University of Groningen. Furthermore, the UMCG is one of the lead institutions in the training courses “Time-lapse imaging and FRET”, “Current protocols in mouse models” and “Computational biology and Bioinformatics “.

The University Medical Center Utrecht (UMC Utrecht, The Netherlands), hosts the project “A biosensor for mitotic spindle checkpoint activity in vitro and in vivo”, and trains one ESR in association with the University of Utrecht. Furthermore, UMC Utrecht is one of the lead institutions in the training courses “Time-lapse imaging and FRET” and “Current protocols in mouse models”.

The University of Manchester (UNIMAN, United Kingdom) hosts the project “Development of biosensors to define how aneuploidy triggers a stress response “, and trains one ESR. Together with the other partners, UNIMAN provides training courses in “Scientific English“ and “Laboratory animals course including ethics”.

The University of Edinburgh (UEDIN, United Kingdom) hosts the project “Using HACs to study the effects of aneuploidy-inducing drugs on kinetochore composition “,and trains one ESR. Together with the other partners, UEDIN provides training courses in “Scientific English“ and “Laboratory animals course including ethics”.

The University of Basel (UNIBAS, Switzerland) hosts the project “Quantitative measurements of mitotic complexes in aneuploid and euploid cells “, thus training 1 PhD candidate. Furthermore, UNIBAS provides the training course “Selected Reaction Monitoring (SRM) “.

The Max Planck Institute of Biochemistry (MPG, Germany) hosts the project “Identification of genes that mediate a p53-regulated arrest in response to aneuploidy “, and trains one ESR in association with the Ludwig Maximilians University München. Furthermore, MPG provides the training courses “Presenting with Impact “ and “Planning and writing your thesis “, and is one of the lead institutions in the training course “Computational biology and Bioinformatics “.

The European Molecular Biology Laboratory (EMBL) in Monterotondo (Italy) hosts the project “Grading CIN in the mammary gland: the in vivo consequences of aneuploidy“, and trains one ESR in association with the University of Heidelberg (Germany). Furthermore, EMBL is one of the lead institutions in the training courses “Current protocols in mouse models”.

The London Research institute-Cancer Research UK (CR-UK, United Kingdom) hosts the project “Defining a mechanistic basis for chromosomal instability in NSCLC “, and trains one ESR in association with the University College London . Together with the other partners, CR-UK provides training courses in “Scientific English“ and “Laboratory animals course including ethics”.

The Netherlands Translational Research Center (NTRC, The Netherlands), hosted the project “In vitro profiling sensitivity towards aneuploidy-modulating drugs “, and will train one Experienced researcher. Furthermore, NTRC is one of the lead institutions in the training course “Drug discovery“, and provides a corporate environment for a 7-8 week internship.

Miltenyi Biotec GMBH (Germany) hosts the project “The relationship between genetic instability and cellular phenotypes on the protein level “, training one experienced researcher. Furthermore, Miltenyi Biotec GMBH provides a corporate environment for a 7-8 week internship.

Syncom B.V. (The Netherlands) is the associated partner of the ITN. It is one of the lead institutions in the “Drug discovery course “. Furthermore, Syncom provides a corporate environment for a 7-8 week internship.